Dermatologic concerns in marginal zone lymphomas


Andrea Ronchi,1 Antonello Sica,2 Paola Vitiello,3 Renato Franco1

1Pathology Unit, Division of Psychological and Bodily Well being and Preventive Drugs, Università degli Studi della Campania “Luigi Vanvitelli”, Naples, 80138, Italy; 2Oncology and Hematology Unit, Division of Precision Drugs, College of Campania Luigi Vanvitelli, Naples, 80131, Italy; 3Dermatology Unit, Division of Psychological and Bodily Well being and Preventive Drugs, Università degli Studi della Campania “Luigi Vanvitelli”, Naples, 80131, Italy

Correspondence: Renato Franco
Pathology Unit, Division of Psychological and Bodily Well being and Preventive Drugs, Università degli Studi della Campania “Luigi Vanvitelli”, Through Luciano Armanni 5, Naples, 80138, Italy
Telephone +390815664084
E mail [email protected]

Summary: Major cutaneous marginal zone lymphoma (PC-MZL) is a B-cell lymphoma that happens within the pores and skin. Though it’s a uncommon illness, PC-MZL accounts for 20-40% of all main cutaneous B-cell lymphomas in Western international locations. The etiology and pathogenesis of PC-MZL is poorly understood, because it often lacks the chromosomal translocations most sometimes current in marginal zone lymphomas from different websites. The prognosis of PC-MZL could be troublesome, as a result of rarity of the illness, and requires the talent of various skilled figures, together with the dermatologist and the pathologist. As well as, the administration of the affected person after the prognosis is complicated and entails the dermatologist, the hematologist, the surgeon, the radiotherapist and the radiologist. The goal of this overview is to explain the scientific and histological findings for the prognosis of PC-MZL, and the cutting-edge for the administration of the affected person.

Key phrases: marginal zone lymphoma, cutaneous lymphoma, Borrelia burgdorferi, immunohistochemistry, dermoscopy

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